Renuva®
The Future of Aesthetic Medicine is Renuva
Renuva Allograft Adipose Matrix
Renuva is a first-of-its-kind treatment that restores age-related volume loss, adds contour and smooths irregularities.
Renuva is an off-the-shelf allograft adipose matrix. When injected, the matrix functions as a scaffold that the body replaces with the patient’s own fat.
On average, Renuva is naturally remodeled by the body within 3 to 6 months post-treatment, leaving only the patient’s fat exactly where desired.
- Ready-to-use - Renuva requires minimal preparation, stores at ambient temperature, does not require refrigeration, and has a maximum shelf life of 15 months.
- Acellular - Renuva is 100% extracellular allograft adipose matrix and is free from human DNA, cells or live components.
- Bio-compatible - Renuva contains the same proteins, collagens, and growth factors as fat.
- Fat-Grafting Alternative - Renuva can obtain similar results to fat-grafting procedures without the need for surgery.
- Minimally Invasive - Renuva is an in-office procedure that requires little to no down time.
Renuva Does Not Migrate.
Results Are Not Hydrophilic.
Renuva stays at the injection site and integrates with the surrounding tissue rather than migrating.
On average, over 3 to 6 months post-treatment, the body gradually replaces Renuva, leaving behind the patient’s own fat cells. Fat cells have been shown to be naturally hydrophobic.
APPLICATION
Renuva is a versatile treatment that helps replace natural-looking volume, anywhere fat already exists in the body.
HANDS
As we age, fat loss in the hands can cause veins and tendons to appear more prominent. Renuva is widely regarded as the gold standard for the treatment of aging hands.
NECK
Fat loss due to aging can contribute to a sagging and crepey appearance in the neck area. Renuva can help restore lost fat smoothing neck lines and creases.
FACE
The natural loss of fat pads in the face can result in flattened cheeks, hollowed temples, and sagging skin. Renuva is ideal for replacing both deep and superficial fat, restoring facial volume and smoothing contours.
BODY
Renuva can smooth out and add contour to desired areas of the body such as hip dips, cellulite dimples or buttocks, as well as smooth irregularities caused by surgery or other reasons.
SAFETY & EFFICACY
For more than 35 years, MTF Biologics, makers of Renuva, has been processing tissue grafts from human donors that are used in a growing array of clinical applications – positively affecting lives across the globe.
- Advanced Processing Techniques - Renuva undergoes an aseptic processing method that removes DNA, cells, and live components while preserving the structural and natural components of the adipose matrix. Renuva passes strict standards for patient safety. With minimal processing, Renuva is tested for endotoxin and for sterility per USP <71>, while preserving the key growth factors needed for adipogenesis and angiogenesis.
- Strict Donor Selection Criteria - Renuva is manufactured by MTF Biologics, who exceed tissue graft industry standards through extremely strict donor acceptance criteria and rigorous processing methods to ensure safety, quality and better outcomes. On average, less than 2% of donated tissue is accepted.
11.5
Million Grafts
MTF Biologics has distributed more than 11.5 million grafts with 0% viral disease transmission.
100%
Aseptic Processing
MTF is still the only tissue bank in the U.S. that uses 100% aseptic processing with no terminal radiation.
100+
Scientific Studies
More than 100 studies to date have supported the efficacy of our tissue processing methods.
BEFORE & AFTERS
Age: 63 | Final Results: 8 Months
Treatment Sessions: 2 | Total Renuva: 12 ccs Renuva Elite Injector: Lori Robertson,
MSN, FNP-C
Age: 52 | Final Results: 4 months Treatment Sessions: 1 | Total Renuva: 3 ccs
Renuva Elite Injector: Rochelle Dela Paz,
APRN-BC, DC
Age: 43 | Final Results: 16 Months
Treatment Sessions: 4 | Total Renuva: 30 ccs
Renuva Elite Injector: Lisa Goodman, PA
Age: 24 | Final Results: 6 Months Treatment Sessions: 2 | Total Renuva: 6 ccs
Renuva Elite Injector: Trevor Larsen, RN
The Science Behind the Matrix
Renuva undergoes a rigorous processing method that removes DNA, cells or live components — retaining the naturally-occurring proteins, collagen, and growth factors found in native fat.
Restoring Volume
Renuva injection after 3 and 12 weeks in athymic mouse.
H&E staining of Renuva injection in an athymic mouse.
3 Weeks Post-Injection with Renuva
Host-cell infiltration and early adipocyte formation around the periphery of the injected graft.
3 Weeks Post-Injection with Renuva
Host-cell infiltration and early adipocyte formation around the periphery of the injected graft.
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