Renuva allograft adipose matrix at Weston Center for Plastic Surgery
Allograft Adipose Matrix

Renuva®Volume RestoredWith Your Own Fat

at Weston Center for Plastic Surgery

A first-of-its-kind injectable scaffold that the body gradually replaces with its own fat. Restores age-related volume loss, refines contour, and smooths irregularities anywhere fat naturally exists.

Overview

The Future of Aesthetic Medicine

Renuva®is a first-of-its-kind treatment that restores age-related volume loss, adds contour, and smooths irregularities. It is an off-the-shelf allograft adipose matrix — when injected, the matrix acts as a scaffold that the body progressively replaces with the patient’s own fat.

On average, Renuva®is naturally remodeled by the body within 3 to 6 months post-treatment, leaving only the patient’s own fat exactly where it’s wanted.

Renuva allograft adipose matrix product

Does Not Migrate

Renuva®stays at the injection site and integrates with the surrounding tissue rather than drifting to neighboring areas, keeping volume exactly where it’s placed.

Not Hydrophilic

Over 3 to 6 months post-treatment, the body gradually replaces Renuva®with the patient’s own fat cells, which have been shown to be naturally hydrophobic.

The Matrix

Renuva® Allograft Adipose Matrix

What makes Renuva® different from a traditional dermal filler or fat-grafting procedure.

Ready-to-Use
Minimal preparation, stores at ambient temperature, no refrigeration required, with a maximum shelf life of 15 months.
Acellular
100% extracellular allograft adipose matrix, free from human DNA, cells, or live components.
Bio-Compatible
Contains the same proteins, collagens, and growth factors as your body's own fat.
Fat-Grafting Alternative
Achieves results similar to a fat-grafting procedure without the need for surgery.
Application

Versatile Treatment Areas

Renuva® helps replace natural-looking volume anywhere fat already exists in the body.

Renuva treatment area: Hands
01
Hands

As we age, fat loss in the hands can cause veins and tendons to appear more prominent. Renuva is widely regarded as the gold standard for the treatment of aging hands.

Renuva treatment area: Neck
02
Neck

Fat loss due to aging can contribute to a sagging, crepey appearance in the neck. Renuva can help restore lost volume and smooth neck lines and creases.

Renuva treatment area: Face
03
Face

Natural loss of facial fat pads can flatten cheeks, hollow temples, and slacken skin. Renuva replaces both deep and superficial fat to restore facial volume and contour.

Renuva treatment area: Body
04
Body

Smooths and contours hip dips, cellulite dimples, the buttocks, and irregularities caused by prior surgery or anywhere fat already exists.

Safety & Efficacy

Thirty-Five Years of Tissue Processing

For more than 35 years, MTF Biologics, the makers of Renuva®, has been processing tissue grafts from human donors across a growing array of clinical applications.

11.5M
Grafts Distributed
MTF Biologics has distributed more than 11.5 million grafts with 0% viral disease transmission.
100%
Aseptic Processing
MTF is still the only tissue bank in the U.S. that uses 100% aseptic processing with no terminal radiation.
100+
Scientific Studies
More than 100 studies to date have supported the efficacy of MTF tissue processing methods.
Donor Selection

Less Than 2% of Referrals Become Releasable Donors

MTF exceeds tissue-graft industry standards through extremely strict donor acceptance criteria and rigorous processing methods.

MTF Biologics donor selection criteria: 301,918 initial referrals filtered down to 4,560 total releasable donors
Patient Results

Before & After

Renuva before and after, age 63
01
Age
63
Final Results
8 Months
Sessions
2
Total Renuva
12 ccs

Renuva Elite Injector — Lori Robertson, MSN, FNP-C

Renuva before and after, age 52
02
Age
52
Final Results
4 Months
Sessions
1
Total Renuva
3 ccs

Renuva Elite Injector — Rochelle Dela Paz, APRN-BC, DC

Renuva before and after, age 43
03
Age
43
Final Results
16 Months
Sessions
4
Total Renuva
30 ccs

Renuva Elite Injector — Lisa Goodman, PA

Renuva before and after, age 24
04
Age
24
Final Results
6 Months
Sessions
2
Total Renuva
6 ccs

Renuva Elite Injector — Trevor Larsen, RN

Actual patients. Individual results may vary.

The Science

Behind the Matrix

Renuva®undergoes a rigorous processing method that removes DNA, cells, and live components while retaining the naturally occurring proteins, collagen, and growth factors found in native fat. When injected, the matrix acts as a scaffold — over 3 to 6 months, the body gradually replaces it with the patient’s own adipose tissue.

Growth Factor Comparison
Growth factor comparison: Renuva retains the same growth factors as human adipose tissue, with no lipids, DNA, live components, or cells
Natural Remodeling
H&E staining of Renuva injection in athymic mouse at 3 and 12 weeks showing host-cell infiltration and adipocyte formation

H&E staining — Renuva injection after 3 and 12 weeks in athymic mouse

3 Weeks Post-Injection

Host-cell infiltration and early adipocyte formation around the periphery of the injected graft.

12 Weeks Post-Injection

The matrix has been substantially replaced by the patient’s own adipose tissue, producing natural, long-lasting volume restoration.

Next Step

Interested in Renuva®?

Schedule a consultation with Dr. Eberle to discuss how Renuva® can restore natural volume and refine contours.

Our Procedures

Discover the full range of surgical and non-surgical treatments tailored to your goals.